Follow us at https://signal.nucleate.xyz/
02:18 - Eric Kelsic's background in physics and systems biology and how it shaped his approach to biological problems
03:57 - Differences in problem-solving between Kelsic's physics/systems biology background and traditional biology backgrounds
06:27 - Learning from working with George Church and his lab's approach to fostering innovation
10:02 - George Church's openness to exploring ideas
12:02 - How Kelsic's experience in George Church's lab led him to start Dyno Therapeutics
19:55 - Kelsic's process of validating the problem of AAV gene delivery and deciding to found a company
24:36 - Leveraging resources like Harvard, the Wyss Institute, and Lab Central in Dyno's early days
28:17 - Overview of AAV gene therapy and Dyno's machine learning-guided approach to engineering improved capsids
38:17 - Kelsic's perspective on partnerships and Dyno's collaborations with industry leaders
41:02 - Kelsic's vision for the future of Dyno and the potential impact of gene therapy