Dr. William Pao joins the Nucleate Podcast to share his inspiring journey from losing his father to cancer to leading groundbreaking cancer research and founding Revelio Therapeutics. He discusses the discovery of EGFR mutations, the stories behind his book Breakthrough, and what it takes to bring life-changing drugs to patients. Tune in for insights on biotech innovation, scientific resilience, and the future of medicine and check out Breakthrough on Amazon or a bookstore near you.
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0:03:41 - Dr. Pao discusses losing his father to colon cancer at age 13, which motivated his career in medicine
0:05:30 - Describes his early academic training, including his PhD work on Gamma Delta T cells
0:09:54 - Begins discussing the EGFR mutation discovery in lung cancer research 0:13:16 - Shares the story of being "scooped" by other researchers when publishing his EGFR mutation findings
0:32:44 - Starts discussing his book "Breakthrough: The Quest for Life-Changing Medicines"
0:42:35 - Tells the serendipitous story of Tylenol's discovery
0:58:38 - Begins discussing entrepreneurship and decision-making in drug development
1:04:29 - Talks about starting his own company, Revelio Therapeutics
1:11:28 - Discusses future trends in medical research and potential breakthrough areas
1:15:52 - Offers final advice about resilience for aspiring entrepreneurs and scientists These timestamps highlight key moments in the conversation about Dr. Pao's career, research, book, and insights into medical innovation.